Structure of PDB 6cnq Chain A

Receptor sequence
>6cnqA (length=68) Species: 9606 (Homo sapiens) [Search protein sequence]
KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYL
GNTVDLSSFDFRTGKMMP
3D structure
PDB6cnq Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
ChainA
Resolution2.151 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R188 S189 P191 R209 R41 S42 P44 R62 PDBbind-CN: Kd=0.9uM
BS02 dna A R166 K167 S168 L170 S171 K186 R19 K20 S21 L23 S24 K39 PDBbind-CN: Kd=0.9uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6cnq, PDBe:6cnq, PDBj:6cnq
PDBsum6cnq
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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