Structure of PDB 6cnp Chain A

Receptor sequence
>6cnpA (length=68) Species: 9606 (Homo sapiens) [Search protein sequence]
KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYL
GNTVDLSSFDFRTGKMMP
3D structure
PDB6cnp Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R166 K167 S168 G169 L170 S171 K186 R19 K20 S21 G22 L23 S24 K39 PDBbind-CN: Kd=0.7uM
BS02 dna A R188 S189 P191 R41 S42 P44 PDBbind-CN: Kd=0.7uM
BS03 CA A P153 L155 P6 L8
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6cnp, PDBe:6cnp, PDBj:6cnp
PDBsum6cnp
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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