Structure of PDB 6cju Chain A

Receptor sequence
>6cjuA (length=390) Species: 869211 (Spirochaeta thermophila DSM 6578) [Search protein sequence]
TYTLVWKVWILAVTLYYAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLLLAPSRLPDLLAALPLDLLVFALHLPSPLSLLSLVRLLKLISVQRSA
TRILSYRINPALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAGTRYLS
AFYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIASLV
SKLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGYEE
REVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIY
GPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAILSEGQFFGEMALI
LRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQIQ
3D structure
PDB6cju Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
ChainA
Resolution3.35 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A G367 E368 M369 R377 T378 A379 G345 E346 M347 R355 T356 A357
BS02 PGW A L32 Y170 L23 Y148
BS03 PGW A S102 L109 F143 G150 S157 L158 S80 L87 F121 G128 S135 L136
BS04 PGW A L137 V141 T182 L221 L115 V119 T160 L199
BS05 PGW A A209 L213 A187 L191
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0044877 protein-containing complex binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6cju, PDBe:6cju, PDBj:6cju
PDBsum6cju
PubMed30028291
UniProtG0GA88

[Back to BioLiP]