Structure of PDB 6cjr Chain A

Receptor sequence
>6cjrA (length=213) Species: 237561 (Candida albicans SC5314) [Search protein sequence]
GETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSD
PSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTK
SFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNA
GGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFVA
YPIQLVVTKEVEK
3D structure
PDB6cjr Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 E0G A A44 K47 M87 N95 L96 F127 Y128 W151 A39 K42 M82 N90 L91 F122 Y123 W146 PDBbind-CN: -logKd/Ki=9.52,Ki=0.30nM
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:6cjr, PDBe:6cjr, PDBj:6cjr
PDBsum6cjr
PubMed30679438
UniProtP46598|HSP90_CANAL Heat shock protein 90 homolog (Gene Name=HSP90)

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