Structure of PDB 6cjj Chain A

Receptor sequence
>6cjjA (length=214) Species: 237561 (Candida albicans SC5314) [Search protein sequence]
QGETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALS
DPSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGT
KSFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESN
AGGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFV
AYPIQLVVTKEVEK
3D structure
PDB6cjj Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
ChainA
Resolution1.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N40 A44 M87 N95 G124 V125 G126 F127 T174 N36 A40 M83 N91 G120 V121 G122 F123 T170 PDBbind-CN: -logKd/Ki=3.90,Kd=125uM
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:6cjj, PDBe:6cjj, PDBj:6cjj
PDBsum6cjj
PubMed30679438
UniProtP46598|HSP90_CANAL Heat shock protein 90 homolog (Gene Name=HSP90)

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