Structure of PDB 6cim Chain A

Receptor sequence
>6cimA (length=611) Species: 10090 (Mus musculus) [Search protein sequence]
HLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNE
HRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGR
QIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASS
VDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVV
VKESCDGMGDVSEKHGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKP
NSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPR
TFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSI
TRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHC
DIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPI
MRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSS
CPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEI
IERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTS
KYLQKFMNAHN
3D structure
PDB6cim Cracking the DNA Code for V(D)J Recombination.
ChainA
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R848 M849 N965 R969 R452 M453 N569 R573
BS02 dna A A441 K844 N850 N852 A47 K448 N454 N456
BS03 dna A T400 A403 Y485 K489 Q495 H501 Q978 T6 A9 Y91 K95 Q101 H107 Q582
BS04 dna A S477 C478 S479 R504 N975 R977 S83 C84 S85 R110 N579 R581
BS05 ZN A C727 H937 H942 C331 H541 H546
BS06 MN A D600 D708 D206 D312
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cim, PDBe:6cim, PDBj:6cim
PDBsum6cim
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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