Structure of PDB 6cht Chain A

Receptor sequence
>6chtA (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
SINALLQAEVLAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQ
VALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSI
RILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQ
VSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKI
DNLLQEMLLG
3D structure
PDB6cht ErbB3-binding protein 1 (EBP1) represses HNF4 alpha-mediated transcription and insulin secretion in pancreatic beta-cells.
ChainA
Resolution3.174 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A K194 N359 E363 K37 N202 E206
External links
PDB RCSB:6cht, PDBe:6cht, PDBj:6cht
PDBsum6cht
PubMed31362984
UniProtP41235|HNF4A_HUMAN Hepatocyte nuclear factor 4-alpha (Gene Name=HNF4A)

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