Structure of PDB 6cf6 Chain A

Receptor sequence
>6cf6A (length=320) Species: 10090 (Mus musculus) [Search protein sequence]
ADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKST
PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELL
LKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSA
VDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS
HETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHN
DVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIIS
LQGFTAAQMGNEAVQQILSE
3D structure
PDB6cf6 Structural basis for tankyrase-RNF146 interaction reveals noncanonical tankyrase-binding motifs.
ChainA
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R361 S363 L368 G371 Y372 K393 L396 N401 Y405 H407 D425 W427 F429 E434 R440 R47 S49 L54 G57 Y58 K79 L82 N87 Y91 H93 D111 W113 F115 E120 R126
External links
PDB RCSB:6cf6, PDBe:6cf6, PDBj:6cf6
PDBsum6cf6
PubMed29604130
UniProtQ6PFX9|TNKS1_MOUSE Poly [ADP-ribose] polymerase tankyrase-1 (Gene Name=Tnks)

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