Structure of PDB 6cf5 Chain A

Receptor sequence
>6cf5A (length=324) Species: 284218 (Influenza A virus (A/Viet Nam/1203/2004(H5N1))) [Search protein sequence]
DPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKKHNGKLCDLDGV
KPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKANPVNDLCYPGDFND
YEELKHLLSRINHFEKIQIIPKSSWSSHEASLGVSSACPYQGKSSFFRNV
VWLIKKNSTYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPTTY
ISVGTSTLNQRLVPRIATRSKVNGQSGRMEFFWTILKPNDAINFESNGNF
IAPEYAYKIVKKGDSTIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPL
TIGECPKYVKSNRLVLATGLRNSP
3D structure
PDB6cf5 A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin.
ChainA
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NHE A L133A S136 S137 W153 Q226 L132 S135 S136 W152 Q225 PDBbind-CN: -logKd/Ki=1.70,Kd>20mM
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cf5, PDBe:6cf5, PDBj:6cf5
PDBsum6cf5
PubMed29610325
UniProtQ6DQ33

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