Structure of PDB 6cex Chain A

Receptor sequence
>6cexA (length=317) Species: 506350 (Influenza A virus (A/Hong Kong/1/1968(H3N2))) [Search protein sequence]
GATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRIL
DGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLR
SLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGS
TYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRS
QQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFK
MRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYV
KQNTLKLATGMRNVPEK
3D structure
PDB6cex A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin.
ChainA
Resolution2.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NHE A G135 S136 W153 G126 S127 W144 PDBbind-CN: -logKd/Ki=1.70,Kd>20mM
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cex, PDBe:6cex, PDBj:6cex
PDBsum6cex
PubMed29610325
UniProtQ91MA7|HEMA_I68A4 Hemagglutinin (Gene Name=HA)

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