Structure of PDB 6cbp Chain A

Receptor sequence

>6cbpA (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGAQMKNPGASVKVSCAPSGYTFTDFYIHWLRQAPGQGLQWMGW
MNPQTGRTNTARNFQGRVTMTRDTSIGTAYMELRSLTSDDTAIYYCTTGG
WISLYYDSSYYPNFDHWGQGTLLTVSGALTQPASVSGSPGQSITISCTGT
KYDVGSHDLVSWYQQYPGKVPKYMIYEVNKRPSGVSNRFSGSKSGNTASL
TISGLRAEDEADYYCCSFGGSATVVCGGGTKVTVH

3D structure

PDB

6cbp HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope.

Chain

Resolution

2.17 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	MAN	A	Y111 Y193 E194	Y111 Y176 E177
BS02	MAN	A	D115 Y190 Y193	D115 Y173 Y176
BS03	MAN	A	R198 P199 S200	R181 P182 S183

External links

PDB	RCSB:6cbp, PDBe:6cbp, PDBj:6cbp
PDBsum	6cbp
PubMed	29549260

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