Structure of PDB 6cau Chain A

Receptor sequence
>6cauA (length=307) Species: 470 (Acinetobacter baumannii) [Search protein sequence]
HHHMRRIKHIHFVGIGGAGMCGIAEVLANQGYKISGSDIKASKTTQQLEE
NGIKVYIGHEAENIKNANVLVVSTAIDPENPEVKAAIEQRIPIVRRAEML
GELMRYRHGIAVAGTHGKTTTTSLLTTMLAEENLDPTYVIGGLLNSTGVN
AALGESRFIVAEADESDASFLYLQPMAAIVTNIDADGSFDKLKDTFVQFL
HNLPFYGLAVVCGDDANIREILPRVGRPVITYGFNEDNDIRAIDVEQDGM
RSHFTVLRKGREPLRLTINQPGLHNVLNALAAIGVATDEGVSDEAISRAL
KGFSGVG
3D structure
PDB6cau UDP-N-acetylmuramate--alanine ligase from Acinetobacter baumannii AB5075-UW with AMPPNP
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K133 L158
Catalytic site (residue number reindexed from 1) K118 L143
Enzyme Commision number 6.3.2.8: UDP-N-acetylmuramate--L-alanine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A H131 G132 K133 T134 T135 N197 H295 N299 H116 G117 K118 T119 T120 N182 H274 N278
BS02 MG A T134 E177 T119 E162
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009058 biosynthetic process
GO:0009252 peptidoglycan biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cau, PDBe:6cau, PDBj:6cau
PDBsum6cau
PubMed
UniProtB7GV74|MURC_ACIB3 UDP-N-acetylmuramate--L-alanine ligase (Gene Name=murC)

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