Structure of PDB 6c9w Chain A

Receptor sequence
>6c9wA (length=396) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
YLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTWIIFAAI
SLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWA
LCASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSHSAFSLKL
ALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFW
YVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSA
LEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAM
IFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSL
3D structure
PDB6c9w Crystal Structure of a ligand-bound LacY-Nanobody Complex.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9PG A M23 R144 W151 E269 H322 M21 R142 W149 E257 H310
Gene Ontology
Molecular Function
GO:0005351 carbohydrate:proton symporter activity
GO:0005515 protein binding
GO:0015293 symporter activity
GO:0015528 lactose:proton symporter activity
GO:0022857 transmembrane transporter activity
GO:0030395 lactose binding
Biological Process
GO:0008643 carbohydrate transport
GO:0015767 lactose transport
GO:0034219 carbohydrate transmembrane transport
GO:0055085 transmembrane transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:6c9w, PDBe:6c9w, PDBj:6c9w
PDBsum6c9w
PubMed30108145
UniProtP02920|LACY_ECOLI Lactose permease (Gene Name=lacY)

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