Structure of PDB 6c99 Chain A

Receptor sequence
>6c99A (length=265) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVW
ENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNT
SVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELT
FLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSF
YPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCI
VQHAGLAQPLRVELE
3D structure
PDB6c99 Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EQY A W29 Q34 G49 S230 G232 W26 Q31 G46 S227 G229 MOAD: Kd=2.4uM
PDBbind-CN: -logKd/Ki=5.62,Kd=2.4uM
External links
PDB RCSB:6c99, PDBe:6c99, PDBj:6c99
PDBsum6c99
PubMed29782488
UniProtP55899|FCGRN_HUMAN IgG receptor FcRn large subunit p51 (Gene Name=FCGRT)

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