Structure of PDB 6c98 Chain A

Receptor sequence
>6c98A (length=262) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVW
ENQVSWYWEKETTDLRIKEKLFLEAFKALGGPYTLQGLLGCELGPDNTSV
PTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFL
LFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYP
PELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ
HAGLAQPLRVEL
3D structure
PDB6c98 Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CYS A P47 C48 P44 C45
BS02 ER7 A W29 Q34 S230 G232 W26 Q31 S225 G227 PDBbind-CN: -logKd/Ki=4.10,Kd~80uM
External links
PDB RCSB:6c98, PDBe:6c98, PDBj:6c98
PDBsum6c98
PubMed29782488
UniProtP55899|FCGRN_HUMAN IgG receptor FcRn large subunit p51 (Gene Name=FCGRT)

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