Structure of PDB 6c4p Chain A

Receptor sequence
>6c4pA (length=344) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EQQADSRHNVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKD
RIAKSMVEEAEASGRIHPSRSTLIEPTSGNTGIGLALIGAIKGYRTIITL
PEKMSNEKVSVLKALGAEIIRTPTAAAWDSPESHIGVAKKLEKEIPGAVI
LDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAVVAGAGTGGTISGI
SKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFVPQV
LDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDH
PELTEDDVIVAIFPDSIRSYLTKFVDDEWLKKNNLWDDDVLARF
3D structure
PDB6c4p Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.22: cystathionine beta-synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PMP A K53 N84 A195 G196 T197 G198 T200 G245 S289 P318 D319 K49 N80 A191 G192 T193 G194 T196 G241 S285 P314 D315
BS02 CA A N183 D186 N187 N179 D182 N183
Gene Ontology
Molecular Function
GO:0004122 cystathionine beta-synthase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019343 cysteine biosynthetic process via cystathionine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6c4p, PDBe:6c4p, PDBj:6c4p
PDBsum6c4p
PubMed29630349
UniProtP32582|CBS_YEAST Cystathionine beta-synthase (Gene Name=CYS4)

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