Structure of PDB 6c3u Chain A

Receptor sequence
>6c3uA (length=138) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
MLSGLNHLTLAVSQLAPSVAFYQQLLGMTLHARWDSGAYLSCGDLWLCLS
LDPQRRVTPPEESDYTHYAFSISEADFASFAARLEAAGVAVWKLNRSEGA
SHYFLDPDGHKLELHVGSLAQRLAACREQPYKGMVFFE
3D structure
PDB6c3u Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H67 E113 H67 E113
BS02 NY2 A Y65 H67 S97 R122 Y131 Y65 H67 S97 R122 Y131 PDBbind-CN: -logKd/Ki=5.40,Kd=4.0uM
BS03 NY2 A H7 T9 W34 Y39 C48 H7 T9 W34 Y39 C48 PDBbind-CN: -logKd/Ki=5.40,Kd=4.0uM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6c3u, PDBe:6c3u, PDBj:6c3u
PDBsum6c3u
PubMed30642934
UniProtA0A0H3GM04

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