Structure of PDB 6c3n Chain A

Receptor sequence
>6c3nA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
SQIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGL
FYSIFTDQLKRNLSVINLDPEINPEGFNILLDFMYTSRLNLRVGNIMAVM
ATAMYLQMEHVVDTCRKFIKASE
3D structure
PDB6c3n Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
ChainA
Resolution2.53171 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EHY A M51 Y58 M45 Y52 PDBbind-CN: -logKd/Ki=2.49,Kd=3.2mM
BindingDB: Kd=3200000nM
BS02 EHY A N21 R24 N15 R18 PDBbind-CN: -logKd/Ki=2.49,Kd=3.2mM
BindingDB: Kd=3200000nM
External links
PDB RCSB:6c3n, PDBe:6c3n, PDBj:6c3n
PDBsum6c3n
PubMed29969259
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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