Structure of PDB 6c33 Chain A

Receptor sequence
>6c33A (length=317) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
TAPILLLDGASMWFRSYFGVPSSIKAPDGRPVNAVRGFIDAISTLVTREK
PRRLVVCRDDDWRPQWRVDLIPSYKAHRVAEPEPDGVPDIEEVPDDLTPQ
VNMILELLDAFGIPTAGAAGFEADDVLGTLSAREERDPVVVVSGDRDLLQ
LVRDEPAPQVRVLYLGRGLAKATKWGPAEVAEQYGVPLDRAGTAYAELAL
LRGDPSDGLPGVAGIGEKTAASLLAKHGSLQNILDAAHDPKSGLSKAHRT
KLLGAVDYIAAAETVVRVATDAPVTFSTPTDTLPLAAGDPARVAELAAAY
GVSSSISRLQTALDQLP
3D structure
PDB6c33 Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D125 D146 D148 D124 D145 D147
BS02 MN A D148 D205 D208 D147 D204 D207
BS03 MN A E84 P85 D90 E83 P84 D89
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004527 exonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0017108 5'-flap endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0033567 DNA replication, Okazaki fragment processing

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Molecular Function
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Biological Process
External links
PDB RCSB:6c33, PDBe:6c33, PDBj:6c33
PDBsum6c33
PubMed29635474
UniProtI7GAS0

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