Structure of PDB 6c2q Chain A

Receptor sequence
>6c2qA (length=345) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SEQQADSRHNVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIK
DRIAKSMVEEAEASGRIHPSRSTLIEPTSGNTGIGLALIGAIKGYRTIIT
LPEKMSNEKVSVLKALGAEIIRTPTAAAWDSPESHIGVAKKLEKEIPGAV
ILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAVVAGAGTGGTISG
ISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFVPQ
VLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCED
HPELTEDDVIVAIFPDSIRSYLTKFVDDEWLKKNNLWDDDVLARF
3D structure
PDB6c2q Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time.
ChainA
Resolution2.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.22: cystathionine beta-synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EVM A K53 T81 S82 N84 T85 Q157 A195 G196 T197 G198 T200 G245 Y248 S289 P318 D319 K50 T78 S79 N81 T82 Q154 A192 G193 T194 G195 T197 G242 Y245 S286 P315 D316
BS02 CA A N183 D186 N187 N180 D183 N184
Gene Ontology
Molecular Function
GO:0004122 cystathionine beta-synthase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019343 cysteine biosynthetic process via cystathionine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6c2q, PDBe:6c2q, PDBj:6c2q
PDBsum6c2q
PubMed29630349
UniProtP32582|CBS_YEAST Cystathionine beta-synthase (Gene Name=CYS4)

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