Structure of PDB 6c1t Chain A

Receptor sequence
>6c1tA (length=67) Species: 9606 (Homo sapiens) [Search protein sequence]
KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYL
GNTVDLSSFDFRTGKMM
3D structure
PDB6c1t Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
ChainA
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R188 S189 P191 R209 M214 R41 S42 P44 R62 M67 PDBbind-CN: Kd=3.2uM
BS02 dna A R166 K167 S168 G169 L170 D176 K186 R188 R19 K20 S21 G22 L23 D29 K39 R41 PDBbind-CN: Kd=3.2uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6c1t, PDBe:6c1t, PDBj:6c1t
PDBsum6c1t
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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