Structure of PDB 6c1a Chain A

Receptor sequence
>6c1aA (length=68) Species: 9606 (Homo sapiens) [Search protein sequence]
GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARY
LGNTVDLSSFDFRTGKMM
3D structure
PDB6c1a Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R166 S168 D176 K186 R20 S22 D30 K40 PDBbind-CN: Kd=7.2uM
BS02 dna A R188 S189 P191 R209 R42 S43 P45 R63 PDBbind-CN: Kd=7.2uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6c1a, PDBe:6c1a, PDBj:6c1a
PDBsum6c1a
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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