Structure of PDB 6bxj Chain A

Receptor sequence
>6bxjA (length=619) Species: 9606 (Homo sapiens) [Search protein sequence]
GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCA
PESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNF
SIQVRQVEDGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQF
AAVQFSTSYKTEFDFSDYVKWKDPDALLKHVKHMLLLTNTFGAINYVATE
VFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTK
ESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIRSKVELEVRDLP
EELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKS
FTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCG
PGWLGSQCECSEEQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGK
YCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMS
SNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKK
FDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQY
YEDSSGKSILYVVEEPECP
3D structure
PDB6bxj Autonomous conformational regulation of beta3integrin and the conformation-dependent property of HPA-1a alloantibodies.
ChainA
Resolution2.092 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A S121 S123 D221 S121 S123 D221
External links
PDB RCSB:6bxj, PDBe:6bxj, PDBj:6bxj
PDBsum6bxj
PubMed30209215
UniProtP05106|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3);
P20701|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

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