Structure of PDB 6bq8 Chain A

Receptor sequence
>6bq8A (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
TAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGE
EGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSA
NIIAEENDVACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDDEKRHAK
3D structure
PDB6bq8 Neutron Crystallography Detects Differences in Protein Dynamics: Structure of the PKG II Cyclic Nucleotide Binding Domain in Complex with an Activator.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.12: cGMP-dependent protein kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 WNU A Q335 K347 Y354 F355 G356 E357 K358 A359 R366 S367 A368 Y404 D412 R415 Q67 K79 Y86 F87 G88 E89 K90 A91 R98 S99 A100 Y136 D144 R147
External links
PDB RCSB:6bq8, PDBe:6bq8, PDBj:6bq8
PDBsum6bq8
PubMed29517905
UniProtQ13237|KGP2_HUMAN cGMP-dependent protein kinase 2 (Gene Name=PRKG2)

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