Structure of PDB 6bpi Chain A

Receptor sequence
>6bpiA (length=206) Species: 9606 (Homo sapiens) [Search protein sequence]
ENLYFQGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGK
SLLSGNHIAYDYHPPADKLYVGSRVVAKYKVWLYAGIVAETPNVKNKLRF
LIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNR
PMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGST
RLEPMF
3D structure
PDB6bpi Crystal structure of SETDB1 Tudor domain with aryl triazole fragment peptide conjugates
ChainA
Resolution1.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.366: [histone H3]-N(6),N(6)-dimethyl-lysine(9) N-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G300 A302 C329 F332 W358 F379 D382 R384 E386 I388 Y389 S392 R394 G107 A109 C136 F139 W165 F186 D189 R191 E193 I195 Y196 S199 R201
External links
PDB RCSB:6bpi, PDBe:6bpi, PDBj:6bpi
PDBsum6bpi
PubMed
UniProtQ15047|SETB1_HUMAN Histone-lysine N-methyltransferase SETDB1 (Gene Name=SETDB1)

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