Structure of PDB 6bjq Chain A

Receptor sequence
>6bjqA (length=598) Species: 515620 ([Eubacterium] eligens ATCC 27750) [Search protein sequence]
NAMLYPVLTQSRLLSDLSGVWDFKLDNGKGFEEKWYEKPLKDADTMPVPA
SYNDLKEGTDFRDHYGWVFYQRNISVPEYVKSQRIVLRCAAVTHYAMIYL
NGKLICEHKGGFLPFEVELNDDLQDGDNLLTIAVNNVIDYTTLPVGGKAN
MMSMGAGASDKPQNNPNFDFFNYCGITRPVKIYTTPETYINDITVTADID
FTKEEPSAVLNYNVEIKKVELFDEEGTKLSETEGSEGTFEISNVRLWQPL
NAYLYKIKVTAGQDVYTLPYGVRSVRVDGTKFLINEKPFYFKGYGKHEDT
FPNGRGINLPMNTKDISIMKWQHANSFRTSHYPYSEEMMRLCDEEGIVVI
DETTAVGVNLQFGGGANFGGERIGTFDKEHGVQTQEHHKDVIRDLISRDK
NHACVVMWSIANEPDSAAEGAYDYFKPLYDLARELDPQKRPCTLVSVQGT
TADTDCSSQLSDVICLNRYYGWYFGGPDLEVSEIGLRKELSDWGKLGKPV
MFTEYGADTVSGLHDTTSVMYTEEYQVEYYEMNNKVFDEFDFVVGEQAWN
FADFATSQSLLRVQGNKKGLFTRDRKPKMVAHYFRNRWSTIPEFGYKT
3D structure
PDB6bjq Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.31: beta-glucuronidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BDP A D172 H343 E425 Y481 Y485 E516 W561 R574 N578 K580 D169 H331 E413 Y469 Y473 E504 W549 R562 N566 K568
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0004566 beta-glucuronidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6bjq, PDBe:6bjq, PDBj:6bjq
PDBsum6bjq
PubMed30062115
UniProtC4Z6Z2

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