Structure of PDB 6bj8 Chain A

Receptor sequence
>6bj8A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
HSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWI
EQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCD
LGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARV
AEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLR
CWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSG
EEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB6bj8 Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 Y9 I66 N70 Y74 E76 S77 N80 Y84 R97 Y99 T143 K146 W147 Y159 W167 Y171 Y5 Y7 I64 N68 Y72 E74 S75 N78 Y82 R95 Y97 T141 K144 W145 Y157 W165 Y169
External links
PDB RCSB:6bj8, PDBe:6bj8, PDBj:6bj8
PDBsum6bj8
PubMed30053426
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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