Structure of PDB 6bj3 Chain A

Receptor sequence
>6bj3A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPW
IEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGC
DLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAR
VAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB6bj3 Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
ChainA
Resolution1.898 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 Y9 I66 F67 N70 E76 S77 N80 Y84 R97 Y99 T143 K146 W147 Q155 Y159 W167 Y171 Y6 Y8 I65 F66 N69 E75 S76 N79 Y83 R96 Y98 T142 K145 W146 Q154 Y158 W166 Y170
External links
PDB RCSB:6bj3, PDBe:6bj3, PDBj:6bj3
PDBsum6bj3
PubMed30053426
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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