Structure of PDB 6bi8 Chain A

Receptor sequence
>6bi8A (length=259) Species: 1235996 (Human betacoronavirus 2c EMC/2012) [Search protein sequence]
NDETKALKELYGPVDPTFLHRFYSLKAAVHGWKMVVCDKVRSLKLSDNNC
YLNAVIMTLDLLKDIKFVIPALQHAFMKHKGGDSTDFIALIMAYGNCTFG
APDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVLQGLKACCYVG
VQTVEDLRARMTYVCQCGGERHRQLVEHTTPWLLLSGTPNEKLVTTSTAP
DFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVL
FPGQKYSSD
3D structure
PDB6bi8 Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease.
ChainA
Resolution2.291 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1672 C1675 C1707 C1709 C130 C133 C165 C167
BS02 AYE A N1590 C1592 N48 C50
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6bi8, PDBe:6bi8, PDBj:6bi8
PDBsum6bi8
PubMed31765674
UniProtK0BWD0

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