Structure of PDB 6bgr Chain A

Receptor sequence
>6bgrA (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETF
RNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIF
GTNGPVDLKKITNFFRGDRCRELTGKPKLFIIQACRGTELDCGIET
3D structure
PDB6bgr Modifications to a common phosphorylation network provide individualized control in caspases.
ChainA
Resolution2.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R64 H121 C163 R36 H93 C135
BS02 AZI A K38 G153 K154 A162 C163 K10 G125 K126 A134 C135
BS03 AZI A E124 G165 E96 G137
BS04 AZI A T92 E94 T64 E66
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6bgr, PDBe:6bgr, PDBj:6bgr
PDBsum6bgr
PubMed29414778
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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