Structure of PDB 6bfl Chain A

Receptor sequence
>6bflA (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]
DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKY
EVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGP
VDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIET
3D structure
PDB6bfl Modifications to a common phosphorylation network provide individualized control in caspases.
ChainA
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R64 H121 C163 R31 H88 C130
BS02 AZI A G66 T67 D68 G33 T34 D35
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6bfl, PDBe:6bfl, PDBj:6bfl
PDBsum6bfl
PubMed29414778
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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