Structure of PDB 6bee Chain A

Receptor sequence
>6beeA (length=542) Species: 10254 (Vaccinia virus WR) [Search protein sequence]
GAMNNTIINSLISIKRSNVFAVDSQIPTLYMPQYISLSGVMTNDNQAIAS
FEIRDQYITALNHLVLSLELPEVKGMGRFGYVPYVGYKCINHVSISSCNG
VIWEIEGEELYNNCINNTIALKHSGYSSELNDISIGLTPNDTIKEPSTVY
VYIKTPFDVEDTFSSLKLSDSKITVTVTFNPVSDIVIRDSSFDFETFNKE
FVYVPELSFIGYMVKNVQIKPSFIEKPRRVIGQINQPTATVTEVHAATSL
SVYTKPYYGNTDNKFISYPGYSQDEKDYIDAYVSRLLDDLVIVSDGPPTG
YPESAEIVEVPEDGIVSIQDADVYVKIDNVPDNMSVYLHTNLLMFGTRKN
SFIYNISKKFSAITGTYSDATKRTIFAHISHSINIIDTSIPVSLWTSQRN
VYNGDNRSAESKAKDLFINDPFIKGIDFKNKTDIISRLEVRFGNDVLYSE
NGPISRIYNELLTKSNNGTRTLTFNFTPKIFFRPTTITANVSRGKDKLSV
RVVYSTMDVNHPIYYVQKQLVVVCNDLYKVSYDQGVSITKIM
3D structure
PDB6bee Structural basis for the inhibition of poxvirus assembly by the antibiotic rifampicin.
ChainA
Resolution3.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 RXM A F168 F486 F163 F481 PDBbind-CN: -logKd/Ki=4.66,Kd=22uM
Gene Ontology
Molecular Function
GO:0042802 identical protein binding
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6bee, PDBe:6bee, PDBj:6bee
PDBsum6bee
PubMed30068608
UniProtP68440|PG125_VACCW Scaffold protein OPG125 (Gene Name=OPG125)

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