Structure of PDB 6bci Chain A

Receptor sequence

>6bciA (length=292) Species: 330483 (Leptographium truncatum) [Search protein sequence]

DNISPWTITGFADAESSFMLTVSKDSKRNTGWSVRPRFRIGLHNKDVTIL
KSIREYLGAGIITSDIDARIRFESLKELEVVINHFDKYPLITQKRADYLL
FKKAFYLIKNKEHLTEEGLNQILTLKASLNLGLSEELKEAFPNTIPAERL
LVTGQEIPDSNWVAGFTAGEGSFYIRIAKNSTLKTGYQVQSVFQITQDTR
DIELMKNLISYLNCGNIRIRKTCVDLVVTNLNDIKEKIIPFFNKNHIIGV
KLQDYRDWCKVVTLIDNKEHLTSEGLEKIQKIKEGMNRGRSL

3D structure

PDB

6bci Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.

Chain

Resolution

2.28 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	E29 S31 M33 S37 R51 R53 L56 H57 R83 K140 N144 L145 R190 T196 L197 Q202 Q204 N230 R232 T252 L254 H293 L294	E15 S17 M19 S23 R37 R39 L42 H43 R69 K126 N130 L131 R176 T182 L183 Q188 Q190 N216 R218 T229 L231 H270 L271
BS02	dna	A	R42 N43 R49 R83 R85 S88 L89 K125 H127 E184 G185 S186 Y188 R190 T210 Q211 D212 R234 C246 K306 N310 R311	R28 N29 R35 R69 R71 S74 L75 K111 H113 E170 G171 S172 Y174 R176 T196 Q197 D198 R220 C223 K283 N287 R288
BS03	CA	A	A28 E184	A14 E170
BS04	CA	A	E29 G183	E15 G169
BS05	CA	A	E29 E184	E15 E170

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:6bci, PDBe:6bci, PDBj:6bci
PDBsum	6bci
PubMed	30357419
UniProt	C7SWF3

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