Structure of PDB 6bcf Chain A

Receptor sequence

>6bcfA (length=288) Species: 330483 (Leptographium truncatum) [Search protein sequence]

NISPWTITGFADAESSFMLTVSKDSKRNTGWSVRPRFRIGLHNKDVTILK
SIREYLGAGIITSDIDARIRFESLKELEVVINHFDKYPLITQKRADYLLF
KKAFYLIKNKEHLTEEGLNQILTLKASLNLGLSEELKEAFPNTIPAERLL
VTGQEIPDSNWVAGFTAAEGSFYIRIAKNSTLKTGYQVQSVFQITQDTRD
IELMKNLISYLNCGNIRIRTCVDLVVTNLNDIKEKIIPFFNKNHIIGVKL
QDYRDWCKVVTLIDNKEHLTSEGLEKIQKIKEGMNRGR

3D structure

PDB

6bcf Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.

Chain

Resolution

2.92 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	E29 M33 R51 R53 H57 R83 N144 L145 R190 T196 L197 K198 Q202 Q204 R232 T252 L254 L294	E14 M18 R36 R38 H42 R68 N129 L130 R175 T181 L182 K183 Q187 Q189 R217 T227 L229 L269
BS02	dna	A	K41 R42 R49 R85 E87 S88 L89 K125 H127 E184 S186 R190 A192 K193 D212 N310	K26 R27 R34 R70 E72 S73 L74 K110 H112 E169 S171 R175 A177 K178 D197 N285
BS03	CA	A	E29 A183	E14 A168
BS04	CA	A	A28 E184	A13 E169
BS05	CA	A	E29 E184	E14 E169

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:6bcf, PDBe:6bcf, PDBj:6bcf
PDBsum	6bcf
PubMed	30357419
UniProt	C7SWF3

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