Structure of PDB 6bce Chain A

Receptor sequence

>6bceA (length=289) Species: 330483 (Leptographium truncatum) [Search protein sequence]

NISPWTITGFADAESSFMLTVSKDSKRNTGWSVRPRFRIGLHNKDVTILK
SIREYLGAGIITSDIDARIRFESLKELEVVINHFDKYPLITQKRADYLLF
KKAFYLIKNKEHLTEEGLNQILTLKASLNLGLSEELKEAFPNTIPAERLL
VTGQEIPDSNWVAGFTAGEGSFYIRIAKNSTLKTGYQVQSVFQITQDTRD
IELMKNLISYLNCGNIRIRTCVDLVVTNLNDIKEKIIPFFNKNHIIGVKL
QDYRDWCKVVTLIDNKEHLTSEGLEKIQKIKEGMNRGRS

3D structure

PDB

6bce Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.

Chain

Resolution

1.75 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	A28 E29 S31 M33 S37 R51 R53 L56 H57 D81 R83 K140 N144 L145 R190 T196 L197 K198 Q202 Q204 N230 R232 R234 T252 N253 L254 H293 L294 R311	A13 E14 S16 M18 S22 R36 R38 L41 H42 D66 R68 K125 N129 L130 R175 T181 L182 K183 Q187 Q189 N215 R217 R219 T227 N228 L229 H268 L269 R286
BS02	dna	A	K41 R42 N43 R49 R83 R85 E87 S88 L89 K125 H127 G183 E184 G185 S186 Y188 R190 K193 Q208 Q211 D212 R234 K274 K306 N310 R311	K26 R27 N28 R34 R68 R70 E72 S73 L74 K110 H112 G168 E169 G170 S171 Y173 R175 K178 Q193 Q196 D197 R219 K249 K281 N285 R286
BS03	CA	A	A28 E184	A13 E169
BS04	CA	A	E29 G183	E14 G168
BS05	CA	A	E29 E184	E14 E169

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:6bce, PDBe:6bce, PDBj:6bce
PDBsum	6bce
PubMed	30357419
UniProt	C7SWF3

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