Structure of PDB 6bbm Chain A

Receptor sequence
>6bbmA (length=405) Species: 373045 (Escherichia coli O111:NM) [Search protein sequence]
PPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQ
ESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIV
RERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFVTGVNTGYDD
LNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEM
PSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYID
DSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAE
ISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDAD
LIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNY
AGPQY
3D structure
PDB6bbm Mechanisms of opening and closing of the bacterial replicative helicase.
ChainA
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A S234 G236 K237 T238 T239 R271 Q281 S171 G173 K174 T175 T176 R208 Q218
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043139 5'-3' DNA helicase activity
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0006270 DNA replication initiation
GO:0010212 response to ionizing radiation
GO:0031297 replication fork processing
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005829 cytosol
GO:0030894 replisome
GO:0033202 DNA helicase complex
GO:1990077 primosome complex
GO:1990100 DnaB-DnaC complex
GO:1990156 DnaB-DnaG complex
GO:1990158 DnaB-DnaC-DnaT-PriA-PriB complex
GO:1990159 DnaB-DnaC-DnaT-PriA-PriC complex
GO:1990160 DnaB-DnaC-Rep-PriC complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6bbm, PDBe:6bbm, PDBj:6bbm
PDBsum6bbm
PubMed30582519
UniProtP0ACB0|DNAB_ECOLI Replicative DNA helicase DnaB (Gene Name=dnaB)

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