Structure of PDB 6b9d Chain A

Receptor sequence
>6b9dA (length=379) Species: 9606 (Homo sapiens) [Search protein sequence]
VKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFAK
GKSFLMDFMLRYMYNQESVDWVGNEPLTGFSTTGIQIWSEIFLINKPDGK
KVAVLLMDTQSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRL
AMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSQHEELQ
NVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILI
PWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYLPHPKSMLQATAEAN
NLAAVATAKDTYNKKMEEICGFLAPNDLQTKHLQLKEESVKLFRGVKKMG
GEEFSRRYLQQLESEIDELYIQYIKHNDS
3D structure
PDB6b9d A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A A77 K78 G79 K80 S81 F82 R217 D218 P272 V276 N279 A49 K50 G51 K52 S53 F54 R168 D169 P221 V225 N228
BS02 MG A K80 D146 Q148 K52 D108 Q110
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6b9d, PDBe:6b9d, PDBj:6b9d
PDBsum6b9d
PubMed29180453
UniProtQ8WXF7|ATLA1_HUMAN Atlastin-1 (Gene Name=ATL1)

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