Structure of PDB 6b62 Chain A

Receptor sequence
>6b62A (length=252) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence]
MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAE
DAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVS
LCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYC
NAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYD
AAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLEL
IK
3D structure
PDB6b62 Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372)
ChainA
Resolution2.003 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E67 D82 L84 D85 T87 D200
Catalytic site (residue number reindexed from 1) E67 D82 L84 D85 T87 D200
Enzyme Commision number 3.1.3.11: fructose-bisphosphatase.
3.1.3.25: inositol-phosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU A G15 R18 Y118 G15 R18 Y118
BS02 GLU A R18 L120 A121 R18 L120 A121
BS03 MG A E67 D82 L84 E67 D82 L84
BS04 MG A D38 T40 P41 E67 E68 D38 T40 P41 E67 E68
BS05 GLU A N151 K164 R165 N151 K164 R165
BS06 GLU A G93 P95 Y97 A121 G93 P95 Y97 A121
Gene Ontology
Molecular Function
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0016787 hydrolase activity
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0046872 metal ion binding
GO:0052832 inositol monophosphate 3-phosphatase activity
GO:0052833 inositol monophosphate 4-phosphatase activity
GO:0052834 inositol monophosphate phosphatase activity
Biological Process
GO:0006020 inositol metabolic process
GO:0007165 signal transduction
GO:0046854 phosphatidylinositol phosphate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6b62, PDBe:6b62, PDBj:6b62
PDBsum6b62
PubMed
UniProtO30298|BSUHB_ARCFU Fructose-1,6-bisphosphatase/inositol-1-monophosphatase (Gene Name=suhB)

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