Structure of PDB 6b58 Chain A

Receptor sequence
>6b58A (length=542) Species: 562 (Escherichia coli) [Search protein sequence]
MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAE
DHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWKTGF
HMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQI
RANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHP
TGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYME
LGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSV
GLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVE
QRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQ
ERFKRVRITDTSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQR
LDEGCTERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPA
3D structure
PDB6b58 Crystal structure of an assembly intermediate of respiratory Complex II.
ChainA
Resolution2.611 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q230 H232 L242 E245 R248 R287 H355 Y356 R390
Catalytic site (residue number reindexed from 1) Q197 H199 L209 E212 R215 R254 H322 Y323 R357
Enzyme Commision number 1.3.5.1: succinate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G11 A12 G13 A15 S36 K37 S43 H44 T45 A48 E49 V157 A191 T192 G193 N204 D211 H355 Y356 G378 E379 R390 S393 S395 L396 L399 G12 A13 G14 A16 S37 K38 S44 H45 T46 A49 E50 V124 A158 T159 G160 N171 D178 H322 Y323 G345 E346 R357 S360 S362 L363 L366
Gene Ontology
Molecular Function
GO:0000104 succinate dehydrogenase activity
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0008177 succinate dehydrogenase (quinone) activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding
Biological Process
GO:0006113 fermentation
GO:0006974 DNA damage response
GO:0009061 anaerobic respiration
GO:0019645 anaerobic electron transport chain
GO:0022900 electron transport chain
GO:0044780 bacterial-type flagellum assembly
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0045283 fumarate reductase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6b58, PDBe:6b58, PDBj:6b58
PDBsum6b58
PubMed29348404
UniProtP00363|FRDA_ECOLI Fumarate reductase flavoprotein subunit (Gene Name=frdA)

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