Structure of PDB 6b50 Chain A

Receptor sequence
>6b50A (length=252) Species: 6183 (Schistosoma mansoni) [Search protein sequence]
GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSD
IIKWQNLIHDSHMTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIY
PNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYK
LSEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGD
GWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPD
LI
3D structure
PDB6b50 Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?
ChainA
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A3P A R17 T18 G19 T20 K21 S22 R115 S123 L203 C226 N228 S229 H230 R19 T20 G21 T22 K23 S24 R110 S118 L198 C221 N223 S224 H225
BS02 OAQ A M38 D91 D144 S157 M40 D86 D139 S152
Gene Ontology
Molecular Function
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:6b50, PDBe:6b50, PDBj:6b50
PDBsum6b50
PubMed
UniProtG4VLE5

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