Structure of PDB 6b4z Chain A

Receptor sequence
>6b4zA (length=256) Species: 6183 (Schistosoma mansoni) [Search protein sequence]
GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSD
IIKWQNLIHDSHMITTLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDL
MNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNS
DFYKLSEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVL
RLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIH
MFPDLI
3D structure
PDB6b4z Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?
ChainA
Resolution1.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A3P A R17 T18 G19 T20 K21 S22 R115 S123 L203 X226 N228 S229 H230 R19 T20 G21 T22 K23 S24 R114 S122 L202 X225 N227 S228 H229
Gene Ontology
Molecular Function
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:6b4z, PDBe:6b4z, PDBj:6b4z
PDBsum6b4z
PubMed
UniProtG4VLE5

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