Structure of PDB 6b06 Chain A

Receptor sequence
>6b06A (length=338) Species: 7141 (Choristoneura fumiferana) [Search protein sequence]
TKKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGL
TTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTR
RGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNE
SLMHTSIGQHLDVTMQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGML
LANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEA
KCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYA
QEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH
3D structure
PDB6b06 Structural characterization of a lepidopteran type-II farnesyl diphosphate synthase from the spruce budworm, Choristoneura fumiferana: Implications for inhibitor design.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K101 F142 D147 D151 R156 D218 K244 F283 D287 D288
Catalytic site (residue number reindexed from 1) K45 F86 D91 D95 R100 D162 K185 F224 D228 D229
Enzyme Commision number 2.5.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C6J A D147 R156 K244 D287 K301 D91 R100 K185 D228 K242
BS02 MG A D147 D151 D91 D95
BS03 MG A D147 D151 D91 D95
BS04 IPE A K101 R104 Q140 R157 D287 K45 R48 Q84 R101 D228
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008299 isoprenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6b06, PDBe:6b06, PDBj:6b06
PDBsum6b06
PubMed29183817
UniProtQ1XAB1

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