Structure of PDB 6azr Chain A

Receptor sequence
>6azrA (length=234) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
LKRIDRMKTEFIANISHELRAPLTAIKAYAETIYNSLGELDLSTLKEFLE
VIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEF
ASSHNVNVLFESNVPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKY
VKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSYEVPGTGLGL
AITKEIVELHGGRIWVESEVGKGSRFFVWIPKDR
3D structure
PDB6azr A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases.
ChainA
Resolution3.628 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A E308 N380 Y384 I416 R430 V431 G441 G443 L446 S470 F472 E65 N137 Y141 I173 R187 V188 G195 G197 L200 S224 F226
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6azr, PDBe:6azr, PDBj:6azr
PDBsum6azr
PubMed29235472
UniProtQ9WZV7

[Back to BioLiP]