Structure of PDB 6aze Chain A

Receptor sequence
>6azeA (length=167) Species: 9606 (Homo sapiens) [Search protein sequence]
TKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQC
QSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYY
GVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQ
CAEVLESFFVQKLKGFK
3D structure
PDB6aze Quantitative and structural assessment of methyllysine analog engagement by cognate binding proteins reveals decrements that can impact qualitative experiment interpretation
ChainA
Resolution2.451 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y10 Y17 E19 S20 F22 Y23 I24 G25 C26 D27 W32 I48 D49 Y4 Y11 E13 S14 F16 Y17 I18 G19 C20 D21 W26 I42 D43
BS02 ZN A C11 C13 H34 C37 C5 C7 H28 C31
BS03 ZN A C26 C29 C53 C56 C20 C23 C47 C50
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6aze, PDBe:6aze, PDBj:6aze
PDBsum6aze
PubMed
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

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