Structure of PDB 6ax3 Chain A

Receptor sequence
>6ax3A (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
GSGVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIA
GCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFD
QIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLV
QVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAP
FLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS
3D structure
PDB6ax3 Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.73: [protein]-arginine 3-hydroxylase.
3.4.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2MR A E238 Q275 W310 S318 H321 D323 W414 E58 Q95 W130 S138 H141 D143 W234
BS02 AKG A Y272 W310 S318 H321 N327 K336 H400 V402 W414 Y92 W130 S138 H141 N147 K156 H220 V222 W234
BS03 ZN A H321 D323 H400 H141 D143 H220
External links
PDB RCSB:6ax3, PDBe:6ax3, PDBj:6ax3
PDBsum6ax3
PubMed29459673
UniProtQ8N371|KDM8_HUMAN Bifunctional peptidase and arginyl-hydroxylase JMJD5 (Gene Name=KDM8)

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