Structure of PDB 6ar2 Chain A

Receptor sequence
>6ar2A (length=134) Species: 9606 (Homo sapiens) [Search protein sequence]
PSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVL
SRNHALVWFDHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGD
IIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEA
3D structure
PDB6ar2 SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R32 K49 V50 L51 S52 R53 S75 N76 V107 D108 V109 E111 H118 R31 K48 V49 L50 S51 R52 S74 N75 V106 D107 V108 E110 H117
External links
PDB RCSB:6ar2, PDBe:6ar2, PDBj:6ar2
PDBsum6ar2
PubMed29063833
UniProtQ14BN4|SLMAP_HUMAN Sarcolemmal membrane-associated protein (Gene Name=SLMAP)

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