Structure of PDB 6aov Chain A

Receptor sequence
>6aovA (length=317) Species: 476294 (Influenza A virus (A/Brisbane/10/2007(H3N2))) [Search protein sequence]
PGATLCLGHHAVPNGTIVKTITNDQIEVTNATELVQSSSTGEICDSPHQI
LDGENCTLIDALLGDPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYASL
RSLVASSGTLEFNNESFNWTGVTQNGTSSACIRRSNNSFFSRLNWLTHLK
FKYPALNVTMPNNEKFDKLYIWGVHHPGTDNDQIFLYAQASGRITVSTKR
SQQTVIPNIGSRPRVRNIPSRISIYWTIVKPGDILLINSTGNLIAPRGYF
KIRSGKSSIMRSDAPIGKCNSECITPNGSIPNDKPFQNVNRITYGACPRY
VKQNTLKLATGMRNVPE
3D structure
PDB6aov A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A R222 N225 R214 N217
BS02 SIA A Y98 T135 S136 S137 W153 L194 S228 Y90 T127 S128 S129 W145 L186 S220
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6aov, PDBe:6aov, PDBj:6aov
PDBsum6aov
PubMed29059230
UniProtB2VNK2

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