Structure of PDB 6an0 Chain A

Receptor sequence
>6an0A (length=433) Species: 1338011 (Elizabethkingia anophelis NUHP1) [Search protein sequence]
HHHHHMQTYINPPLSEWKNLIQRPVQKAEDLQNIVLTVFEDIKNEKDKAL
INYTKKFDKAYLTDIRVSSDEITAAIALVSDELIQAIQMAASNIEKFHAS
QKENKNIIETTEGVNCWREARPIENIGIYIPGGSAPLFSTVLMLGIPAQL
AGCKNITLCTPPDESGNINPAILYTANLIGIKNIYKAGGIQAIGAMTFGT
ETIEKADKIFGPGNQYVTAAKQIAQNFGVAIDMPAGPSEVLVIADTTANP
EFVAADLLSQAEHGADSQVILLTTDENILQQTLMQVENQLTQLPRKSIAS
QALLQSRGIVLDSIEKCIAFSNLYAPEHLILAIENTENYTDKITSAGSVF
LGNFSCESAGDYASGTNHTLPTNGYARNYSGVSLDSFIKKITFQKVTKKG
IQNIGPGIEKMAEAEELFAHKHAVSVRLKSLNS
3D structure
PDB6an0 Crystal Structure of Histidinol Dehydrogenase from Elizabethkingia anophelis
ChainA
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q255 H258 E322 H323 D356 H415
Catalytic site (residue number reindexed from 1) Q260 H263 E327 H328 D361 H420
Enzyme Commision number 1.1.1.23: histidinol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H258 D356 H263 D361
BS02 HIS A E98 N99 K100 R113 E114 A115 K385 E103 N104 K105 R118 E119 A120 K390
Gene Ontology
Molecular Function
GO:0004399 histidinol dehydrogenase activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046872 metal ion binding
GO:0051287 NAD binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6an0, PDBe:6an0, PDBj:6an0
PDBsum6an0
PubMed
UniProtA0A077ECF2

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