Structure of PDB 6ajr Chain A

Receptor sequence
>6ajrA (length=204) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
AGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIG
EQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRA
AGGKRRIHKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGND
FRVTQHRGEVLHVDVPPALVATVHPSSLLRGPKEERESAFAGLVDDLRVA
ADVR
3D structure
PDB6ajr Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision.
ChainA
Resolution1.341 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SF4 A C24 G26 C27 Y30 K94 H95 C120 W123 C23 G25 C26 Y29 K93 H94 C119 W122
BS02 URA A E52 Q53 E58 P64 F65 N91 H178 E51 Q52 E57 P63 F64 N90 H174 PDBbind-CN: -logKd/Ki=4.31,Kd=48.5uM
Gene Ontology
Molecular Function
GO:0004844 uracil DNA N-glycosylase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0097506 deaminated base DNA N-glycosylase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function

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Biological Process
External links
PDB RCSB:6ajr, PDBe:6ajr, PDBj:6ajr
PDBsum6ajr
PubMed31101917
UniProtA0QP43

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