Structure of PDB 6agz Chain A

Receptor sequence
>6agzA (length=386) Species: 4919 (Pichia) [Search protein sequence]
PLADTNLFKPIKVGKIELKNRLVFPPTTRFRNTSDFVATDSMLSYYSQRA
ENNGGLLITEATFGAPQFGLYQNGPMIYTDRQVEAWKKIVEEVHKKGSHI
SMQLWNLGRAADPKLLKEHGLPFLAPSALYFSEESKKAAEEAGNEVQAMT
LEQIEQTKKDYVNAAKNAIQKAGFDMVEVHSAHGYLLDQFIQTTANKRTD
KYGGSIENRARLLLEVIDLVIEAVGADHVAVRLSPYATFQGSGGVDAEVH
PIAQFGYILSELERRAKEGKRLAYVSIVEPEDNSWMLQIWKGVVLRSGGY
LSEKGIAHLIKDVNADDRTLIGCSRYFTSNPDLPNRLRDGLPLTPYDRSR
FYKIFSNDGYLTWGKYGEPEQPSDSAIALKTPQPLA
3D structure
PDB6agz Structural basis of different substrate preferences of two old yellow enzymes from yeasts in the asymmetric reduction of enone compounds.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) T35 H187 H190 Y192 R239 Q247
Catalytic site (residue number reindexed from 1) T28 H180 H183 Y185 R232 Q240
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A P33 T34 T35 A68 Q110 H187 R239 G317 C342 S343 R344 F370 Y371 P26 T27 T28 A61 Q103 H180 R232 G298 C323 S324 R325 F351 Y352
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003959 NADPH dehydrogenase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:6agz, PDBe:6agz, PDBj:6agz
PDBsum6agz
PubMed30445889
UniProtA0A5H1ZR30

[Back to BioLiP]